Ilumya (tildrakizumab) is a prescription medication used to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. It is a monoclonal antibody that works by blocking the p19 subunit of interleukin-23 (IL-23), a cytokine that plays a key role in the development and progression of psoriasis.
Uses
Ilumya is used to treat moderate to severe plaque psoriasis in adults. Plaque psoriasis is a chronic autoimmune disease that causes red, scaly patches of skin to form. Ilumya can help to clear these patches and improve the appearance and comfort of the skin.
Storage Conditions
Ilumya should be stored in the refrigerator at 36°F to 46°F (2°C to 8°C). Do not freeze. Ilumya can be kept at room temperature for up to 24 hours.
Mechanism of Action
Ilumya is a monoclonal antibody that binds to the p19 subunit of IL-23 and blocks its interaction with the IL-23 receptor. IL-23 is a cytokine that plays a key role in the development and progression of psoriasis. By blocking IL-23, Ilumya can help to reduce inflammation and improve the symptoms of psoriasis.
How to Use
Ilumya is administered by subcutaneous injection every 12 weeks. The recommended dose is 100 mg. Ilumya should be injected by a healthcare professional.
Important Safety Information
Ilumya can increase the risk of serious infections, including tuberculosis. Before starting Ilumya, your doctor will test you for tuberculosis. Ilumya can also reactivate latent tuberculosis infection.
Ilumya can also increase the risk of other side effects, such as:
- Allergic reactions
- Inflammatory bowel disease (IBD)
- Psoriasis worsening
- Injection site reactions
- Upper respiratory tract infections
- Headache
- Diarrhea
- Nausea
- Fatigue
Indications
Ilumya is indicated for the treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Precautions
Ilumya should be used with caution in patients with a history of serious infections, tuberculosis, IBD, or other autoimmune diseases.
Ilumya should not be used in patients who have a history of severe allergic reactions to Ilumya or other biologic medications.
Interactions
Ilumya may interact with other medications, including live vaccines and biologic medications. Be sure to tell your doctor about all of the medications you are taking before starting Ilumya.
Contraindications
Ilumya is contraindicated in patients with a history of severe allergic reactions to Ilumya or other biologic medications.
Overdose
There is no known overdose of Ilumya.
Side Effects
The most common side effects of Ilumya are upper respiratory tract infections, headache, diarrhea, nausea, fatigue, and injection site reactions.
More serious side effects of Ilumya include serious infections, IBD, psoriasis worsening, and allergic reactions.
If you experience any side effects while taking Ilumya, be sure to tell your doctor.
Fiona MacLeod –
Ilumya has given me results I didn’t think were possible. The itching and redness that used to affect my daily life are now minimal, and my skin continues to improve with ongoing treatment. My confidence has returned, and I no longer avoid outdoor activities or social gatherings because of my psoriasis. I’m incredibly thankful for this medication.
Andrei Popescu –
Since beginning Ilumya, my psoriasis has steadily improved with each passing month. The thick plaques on my elbows and legs have faded considerably, and my skin feels smoother and healthier overall. I appreciate how effective the treatment has been, and my follow-up appointments have shown consistent progress. I couldn’t be more satisfied.
Mariana Lopes –
Ilumya has exceeded all of my expectations. My skin is clearer than it has been in years, and I no longer feel embarrassed in social situations. The irritation and flaking have decreased significantly, and I spend much less time worrying about my psoriasis. It’s been a life-changing experience, and I’m grateful for this treatment.
Jonas Eriksen –
I’ve tried several treatments over the years, but Ilumya has been the most effective for me. My psoriasis plaques have become much smaller, and the constant itching has almost disappeared. The improvement has been steady, and my dermatologist has been very pleased with my progress. This medication has truly improved my quality of life.
Bianca Romano –
Ilumya has been an incredible treatment for my plaque psoriasis. After struggling with persistent plaques for years, I finally started seeing noticeable improvements within a few months. The redness and scaling gradually faded, and my skin feels much healthier now. I have much more confidence wearing short sleeves again, and I’m extremely happy with the results.