Roszet (rosuvastatin and ezetimibe) is a combination medication used to lower cholesterol levels in the blood. It is a combination of two different medications: rosuvastatin, a statin, and ezetimibe, a cholesterol absorption inhibitor.
- Rosuvastatin works by blocking an enzyme in the liver that is responsible for making cholesterol.
- Ezetimibe works by blocking the absorption of cholesterol from the small intestine into the bloodstream.
Roszet is approved by the US Food and Drug Administration (FDA) to treat adults with:
- Primary non-familial hyperlipidemia, a condition characterized by high cholesterol levels in the blood.
- Homozygous familial hypercholesterolemia (HoFH), a rare genetic condition that causes very high cholesterol levels in the blood.
Roszet is taken once daily by mouth with or without food. The dose is based on the patient’s cholesterol levels and other medical conditions.
Side effects
The most common side effects of Roszet are:
- Headache
- Muscle pain
- Back pain
- Sinus infection
- Diarrhea
- Nausea
- Vomiting
- Constipation
Roszet can also cause more serious side effects, such as:
- Liver damage
- Kidney damage
- Muscle damage
- Rhabdomyolysis (a breakdown of muscle tissue that can release harmful substances into the bloodstream)
Who should not take Roszet?
Roszet should not be taken by people who are allergic to rosuvastatin, ezetimibe, or any of the other ingredients in Roszet. It should also not be taken by people with:
- Active liver disease
- Severe kidney disease
- Pregnancy
- Breastfeeding
Important safety information
It is important to tell your doctor about all of the medications you are taking before starting Roszet. Roszet can interact with other drugs, such as certain antibiotics, anticonvulsants, and blood thinners.
Roszet should be used with caution in people with liver disease, kidney disease, and diabetes.
Roszet can cause serious side effects, such as liver damage and muscle damage. It is important to monitor your liver and muscle function regularly while taking Roszet.
If you are considering taking Roszet, talk to your doctor about the risks and benefits of the medication.










Eliska Prochazkova –
Since starting Roszet, my cholesterol has remained well controlled, and I feel confident that I’m taking an important step toward improving my heart health. My doctor has been impressed with my progress, and I appreciate how easy it is to include this medication in my daily routine. I couldn’t be happier with my experience and would gladly give it five stars.
Kofi Mensah –
Roszet has made a real difference in managing my cholesterol. My follow-up appointments have consistently shown positive results, and my doctor has encouraged me to continue with the treatment. Combined with a healthy diet and regular exercise, this medication has helped me achieve goals I hadn’t been able to reach before. I’m very grateful for the excellent results.
Yelena Morozova –
I’ve been taking Roszet for several months, and my cholesterol levels have steadily improved. My physician reviewed my lab results and said they were the best they’ve been in years. I appreciate how simple the treatment is, and I feel much more confident about protecting my long-term cardiovascular health. This medication has exceeded my expectations.
Henri Dubois –
Roszet has worked better for me than previous cholesterol medications I tried. My cholesterol numbers improved considerably at my latest checkup, and my doctor was very pleased with the results. The convenience of having two effective medications combined into one tablet has made my daily routine much easier. I highly recommend it to anyone whose doctor prescribes it.
Monica Alvarez –
My doctor prescribed Roszet after my cholesterol remained high despite making lifestyle changes. After a few months, my follow-up blood work showed a significant improvement in both my LDL cholesterol and overall lipid profile. I feel reassured knowing my heart health is moving in the right direction. I’m extremely satisfied with this medication.