Buy AROMASIN 25mg TABLET (EXEMESTANE) – PFIZER Online

Chemical name: (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
Formula: C20H24O2

Product Overview:

Aromasin (Exemestane) is an oral medication manufactured by Pfizer, designed specifically for the treatment of breast cancer. Each package contains 30 tablets, with each tablet providing a 25mg dose of Exemestane, the active ingredient.

Indications:

Aromasin is primarily indicated for:

• Postmenopausal women with estrogen-receptor-positive early breast cancer who have received two to three years of tamoxifen and are switched to Aromasin for completion of a total of five consecutive years of adjuvant hormonal therapy.
• Advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.

Mechanism of Action:

Exemestane is an irreversible, steroidal aromatase inactivator. It works by binding to the aromatase enzyme, which is involved in estrogen production, thereby inhibiting the conversion of androgens to estrogens. This reduction in estrogen levels helps to slow or reverse the growth of hormone-sensitive breast cancer cells.

Dosage and Administration:

• The recommended dosage of Aromasin is one 25mg tablet taken once daily, preferably after a meal.
• For postmenopausal women with early breast cancer, treatment should continue until completion of five years of adjuvant hormonal therapy, or until tumor relapse occurs.
• In the case of advanced breast cancer, treatment should continue until tumor progression is evident.

Precautions:

• Aromasin should be used with caution in patients with hepatic or renal impairment.
• Bone density monitoring is advised, as Aromasin may decrease bone mineral density.
• Patients should be monitored for signs of hypercholesterolemia, as Aromasin can increase cholesterol levels.

Side Effects:

Common side effects include:

• Hot flashes
• Fatigue
• Joint pain
• Headache
• Insomnia
• Increased sweating

Less common but serious side effects may include:

• Osteoporosis and fractures
• Hepatic impairment
• Cardiovascular events

Drug Interactions:

• Aromasin may interact with medications such as rifampicin, phenytoin, and carbamazepine, which induce CYP3A4 and could decrease the effectiveness of Exemestane.
• Concurrent use with estrogen-containing therapies should be avoided as they could diminish Aromasin’s effectiveness.

Storage:

• Store Aromasin tablets at room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep in the original packaging to protect from moisture.
• Keep out of reach of children.

Packaging:

Each pack of Aromasin contains 30 tablets, with each tablet containing 25mg of Exemestane.

Manufacturer:

Pfizer Inc., a leading global pharmaceutical company, ensures the quality and efficacy of Aromasin through rigorous manufacturing and quality control processes.

Conclusion:

Aromasin (Exemestane) 25mg tablets by Pfizer provide an effective treatment option for postmenopausal women with hormone-sensitive breast cancer. Its specific mechanism of action, combined with the trust and reliability of the Pfizer brand, makes Aromasin a critical component in breast cancer therapy. Always consult with a healthcare provider to ensure this medication is right for you.