Voxzogo (vosoritide) is a prescription medicine used to increase linear growth in children with achondroplasia aged 5 years and older with open growth plates. Achondroplasia is a genetic condition that causes severely short stature and disproportionate growth.
Voxzogo is a modified type C natriuretic peptide (CNP) that binds to the natriuretic peptide receptor-B (NPR-B) to promote bone growth.
Voxzogo is given as a once-daily injection under the skin. The dose is based on the patient’s body weight.
How effective is Voxzogo?
In clinical studies, Voxzogo was shown to be effective in increasing linear growth in children with achondroplasia. In one study, children treated with Voxzogo grew an average of 1.59 inches per year, compared to 0.64 inches per year in children who received a placebo.
What are the side effects of Voxzogo?
The most common side effects of Voxzogo are:
- Injection site reactions
- Vomiting
- Decreased blood pressure
- Headache
- Fatigue
- Diarrhea
- Upper respiratory tract infection
Voxzogo can also cause more serious side effects, such as:
- Allergic reactions
- Decreased liver function
- Decreased kidney function
- Increased risk of infection
Who should not take Voxzogo?
Voxzogo should not be taken by people who are allergic to vosoritide or any of the other ingredients in Voxzogo.
Important safety information
It is important to tell your doctor about all of the medications you are taking before starting Voxzogo. Voxzogo can interact with other drugs, such as certain antibiotics and anticonvulsants.
Voxzogo should be used with caution in people with liver disease or kidney disease.
Voxzogo can cause serious side effects, such as allergic reactions and decreased liver function. It is important to monitor your liver function regularly while taking Voxzogo.
If you are considering taking Voxzogo, talk to your doctor about the risks and benefits of the medication.
MD_ParentSupport –
Voxzogo has been a blessing for our child’s development. The progress in height and flexibility has been steady and medically verified. What makes it even better is how well-tolerated it is — no issues or discomfort after injections. Seeing tangible improvements in growth has been such a relief for our whole family. It’s worth every bit of effort for the results we’ve seen.
Emily Johnson –
Our child has been on Voxzogo for several months, and the results have been remarkable. Growth rate has improved, posture looks better, and overall energy levels are up. The medication is easy to use, and we’ve experienced no serious side effects. It’s giving our child both physical improvement and emotional confidence. We’re incredibly grateful for this innovation in treatment.
DP_FamilyHope –
I’m amazed at how effective Voxzogo has been. It’s clear that it’s working as intended — steady growth, more confidence, and a better quality of life. We were initially nervous about starting the treatment, but it has exceeded every expectation. The improvements have been consistent and well-monitored by our healthcare team. Truly a breakthrough therapy for those who need it.
Sarah Mitchell –
Voxzogo has been life-changing for our family. After months of treatment, we’ve seen noticeable growth progress and better mobility in our child. It’s incredible to watch real, measurable improvements without any major side effects. The administration process is straightforward, and our doctor has been pleased with the consistent results. This medication has given us hope and visible progress we didn’t think possible before.