Overview
Tilidin 20x 100/8mg is a prescription medication manufactured by Sandoz, designed for effective pain management. It contains Tilidine, a potent opioid analgesic, and Naloxone, an opioid antagonist. This combination is formulated to provide significant pain relief while minimizing the risk of opioid misuse and dependence.
Composition
Each tablet of Tilidin 20x 100/8mg contains:
- Tilidine: 100 mg
- Naloxone: 8 mg
Other inactive ingredients may include binders, fillers, and coloring agents used to ensure tablet stability and ease of ingestion.
Mechanism of Action
- Tilidine: Tilidine is an opioid analgesic that works by binding to opioid receptors in the central nervous system, altering the perception of and response to pain. It helps in managing moderate to severe pain effectively.
- Naloxone: Naloxone is included to counteract the effects of Tilidine if misused. It acts as an opioid antagonist, blocking the opioid receptors and thereby preventing the euphoric effects of Tilidine when taken in excess or via routes other than prescribed.
Indications
Tilidin 20x 100/8mg is indicated for the treatment of:
- Moderate to severe pain, where the use of an opioid analgesic is appropriate and other pain management strategies are insufficient.
Dosage and Administration
- The typical dosage is determined by a healthcare professional based on the patient’s condition, severity of pain, and response to treatment.
- Tablets should be taken orally, with or without food, as directed by the physician.
- It is crucial to follow the prescribed dosage regimen to minimize the risk of dependency and adverse effects.
Contraindications
- Hypersensitivity to Tilidine, Naloxone, or any other component of the medication.
- Patients with severe respiratory depression or acute asthma.
- Individuals with gastrointestinal obstruction, including paralytic ileus.
Warnings and Precautions
- Addiction, Abuse, and Misuse: Despite the presence of Naloxone, there is still a risk of opioid addiction, abuse, and misuse. Monitor patients closely for signs of abuse and addiction.
- Respiratory Depression: Serious, life-threatening, or fatal respiratory depression may occur. Monitor for respiratory depression, especially during the initiation of treatment or following a dosage increase.
- Risk from Concomitant Use with Benzodiazepines or Other CNS Depressants: Profound sedation, respiratory depression, coma, and death may result from the concomitant use of opioids with benzodiazepines or other CNS depressants.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Dizziness or light-headedness
- Constipation
- Sweating
Severe side effects requiring immediate medical attention:
- Severe respiratory depression
- Severe hypotension
- Serotonin syndrome (if taken with serotonergic drugs)
- Adrenal insufficiency
- Anaphylactic reactions
Storage
- Store at room temperature away from moisture, heat, and light.
- Keep out of reach of children.
Packaging
Tilidin 20x 100/8mg is available in blister packs containing 20 tablets each, ensuring the medication is protected from environmental factors and easy to dispense.
Sarah Thompson –
Tilidin by Sandoz is a reliable, pharmaceutical-grade pain reliever that truly works. It provides smooth, steady pain relief and a noticeable boost in comfort without making me feel heavy or sedated. It’s also easy on the stomach and has a consistent effect each time. This product is an excellent choice for anyone needing dependable, controlled pain management.
Daniel Wright –
This Tilidin formula is perfect for anyone who needs pain relief but still wants to stay clear-headed. It eases my joint pain efficiently, allowing me to work, move, and sleep better. The 100/8mg ratio is spot-on — strong enough to manage discomfort but gentle on the system. Sandoz really knows how to deliver a high-quality, well-formulated product.
Laura Jenkins –
I’ve tried many different pain medications, but Tilidin 100/8mg from Sandoz stands out for its consistency. It takes effect fast and keeps the pain away for hours without harsh side effects. I appreciate how it helps me stay alert and functional throughout the day. The quality from Sandoz is excellent — every tablet feels reliable and precise.
Michael Foster –
Tilidin from Sandoz is an incredible option for managing moderate to strong pain. It works quickly and provides long-lasting relief without making me feel overly drowsy or foggy. I’ve used it for chronic back pain, and it’s been a game changer compared to other pain medications. It feels smooth, effective, and well-balanced — truly pharmaceutical-grade quality.
Rick Hampton –
Tilidin works quickly and keeps pain under control for hours. It’s a dependable option when you need consistent relief.
Ronald A. Fain –
Tilidin provides fast and effective pain relief without making me too sleepy. Perfect for staying active while managing discomfort.
W. Howard –
Tilidin 20x 100/8mg has been very effective in managing my pain without causing excessive drowsiness. The dosage is well-balanced, providing strong relief while allowing me to stay functional throughout the day. The tablets are easy to take, and the product from Sandoz is consistently reliable and high quality. Highly recommend for those needing dependable pain management.