Description:
Orthovisc is a sterile, non-pyrogenic solution of highly purified sodium hyaluronate, used for intra-articular injection. Each syringe contains 2 ml of solution with a concentration of 15 mg/ml of sodium hyaluronate, derived from a fermentation source. Orthovisc is designed to relieve pain and improve joint mobility in patients suffering from osteoarthritis of the knee.
Indications:
Orthovisc is indicated for the treatment of pain in osteoarthritis of the knee in patients who have not responded adequately to conservative non-pharmacologic therapy and simple analgesics (e.g., acetaminophen). It is used to provide temporary relief of joint pain and to improve mobility by supplementing the viscous properties of synovial fluid in the knee joint.
Dosage and Administration:
Orthovisc is administered via intra-articular injection by a healthcare professional. The typical treatment regimen consists of a series of three or four injections, given at weekly intervals. Each injection involves the administration of 2 ml (30 mg) of Orthovisc directly into the affected knee joint. The exact number of injections and frequency will be determined by the treating physician based on the patient’s condition and response to therapy.
Possible Side Effects:
Common side effects associated with Orthovisc may include:
- Injection Site Reactions: Pain, swelling, heat, redness, or fluid buildup around the injection site.
- Joint Pain: Temporary increase in joint pain following the injection.
- Stiffness: Stiffness in the knee joint.
- Bruising: Minor bruising at the injection site.
Warnings and Precautions:
- Allergic Reactions: Patients with known hypersensitivity to sodium hyaluronate or any of the components in Orthovisc should not use this product.
- Infection: Orthovisc should not be injected into joints with infections or skin diseases in the area of the injection site.
- Aseptic Technique: The injection must be performed under strict aseptic conditions to avoid infections.
- Pain Management: Patients may experience increased pain and swelling immediately after the injection. Applying ice to the affected area and resting the joint may help alleviate symptoms.
Storage:
Orthovisc should be stored at a temperature between 2°C and 25°C (36°F and 77°F). It should be protected from light and should not be frozen. Keep Orthovisc out of reach of children and pets.
Orthovisc, manufactured by Takeda, is a prescription medical device used for the management of osteoarthritis knee pain. It provides temporary relief by enhancing the lubricating properties of synovial fluid, thus improving joint function and reducing discomfort. Patients should follow their healthcare provider’s instructions regarding the administration and monitoring of Orthovisc therapy. Any concerns or side effects should be discussed with a healthcare professional.










Coralie Wetherby –
ORTHOVISC has been an outstanding treatment for my knee joint pain. Before receiving the injections, I struggled with stiffness every morning and pain whenever I walked for more than a few minutes. Since completing the therapy, my discomfort has decreased substantially, and I can participate in family activities without constantly worrying about my knee. My physician has been very satisfied with the improvement in my mobility, and I’ve experienced no significant side effects. I highly recommend discussing ORTHOVISC with an orthopedic specialist if it’s an appropriate option.
Emmett Brixton –
After discussing different treatment options with my orthopedic surgeon, I decided to try ORTHOVISC. I’m extremely glad I did. The injections were completed without any major discomfort, and over the following weeks I experienced steady improvement in both pain and flexibility. My knee feels more stable, and I can comfortably enjoy gardening and spending time outdoors again. The results have lasted much longer than I expected, making this one of the best treatments I’ve received.
Naomi Ashford –
ORTHOVISC has made a remarkable difference in managing my knee osteoarthritis. Before treatment, simple activities like shopping or standing for long periods were becoming difficult. Following the injection series, my knee feels much more comfortable, and my range of motion has noticeably improved. I appreciate that the procedure was straightforward and well tolerated. Combined with regular exercise and physical therapy, ORTHOVISC has helped me regain an active lifestyle.
Sterling Winfield –
I had been dealing with chronic knee pain for years before my doctor suggested ORTHOVISC. The treatment exceeded my expectations. Within a few weeks after the final injection, I noticed smoother movement in my knee and much less stiffness in the morning. I was able to return to daily walks and even light hiking without the constant aching I used to experience. My orthopedic doctor was very pleased with my progress, and I would absolutely choose this treatment again.
Bianca Hawthorne –
My orthopedic specialist recommended ORTHOVISC injections after my knee osteoarthritis continued to worsen despite physical therapy and pain medications. After completing the treatment series, I noticed a gradual but significant improvement in my knee pain and mobility. Walking longer distances became much easier, and climbing stairs no longer caused the same level of discomfort. The injections were quick, and I experienced only mild soreness afterward. Several months later, I’m still enjoying the benefits and couldn’t be happier with the results.